International Seven Journal of Health Research
type: channel
description: The International Seven Journal of Health (ISJH)- ISSN- 2764-9415 is a journal dedicated to the publication of articles and studies related to the health area on an international basis, with bilingual publications in English, Spanish and Portuguese.
publisher: Isabele de Souza Carvalho
language: en
publication name: International Seven Journal of Health Research
issn: 2764-9415
items: INFANT BACTERIAL MENINGITIS: DIAGNOSTIC, THERAPEUTIC, AND PROGNOSTIC CHALLENGES IN RECENT CASE REPORTS
items: EXCESSIVE SCREEN USE: PREVALENCE AND RISKS ASSOCIATED WITH CHILD DEVELOPMENT
items: MULTIDISCIPLINARY TREATMENT OF BONE SARCOMAS: OSTEOSARCOMA, CHONDROSARCOMA, AND EWING SARCOMA
items: RISKY SEXUAL BEHAVIORS IN UNIVERSITY STUDENTS ON THE AMERICAN CONTINENT
items: SPIRULINA (ARTHROSPIRA PLATENSIS): AN ALTERNATIVE SOURCE OF NUTRIENTS - A REVIEW
items: CONSCIOUS SEDATION IN DENTAL PRACTICE: CLINICAL PHARMACOLOGICAL PERSPECTIVES
items: ORAL SQUAMOUS PAPILLOMA ASSOCIATED WITH HPV: DIFFERENTIAL DIAGNOSIS WITH OTHER VERRUCOUS LESIONS
items: Template para Autores
items: HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FINDINGS OF PLACENTAS IN PREGNANT PATIENTS WITH SARS-COV-2
items: THE ROLE OF FORENSIC ANTHROPOLOGISTS: A REVIEW OF THE SITUATION IN BRAZIL
items: EFFECTIVENESS OF PRIMARY HEALTH CARE IN THE CONTROL OF PERIODONTITIS: A CRITICAL REVIEW WITH EMPHASIS ON HEALTH PROMOTION STRATEGIES
items: THE ROLE OF THE PHYSICIAN IN THE MANAGEMENT OF STROKE: PATHOPHYSIOLOGY, DIAGNOSIS AND CURRENT THERAPEUTIC APPROACHES
items: GENES INVOLVED AND COMBINATION OF PHENOTYPIC HETEROGENEITY IN PATIENTS DIAGNOSED WITH AUTISM SPECTRUM DISORDER (ASD): A LITERATURE REVIEW
items: FROM PSYCHOSIS TO THE AUTISM SPECTRUM: A BRIEF HISTORY OF THE DIAGNOSTIC TRANSITION IN THE FIELD OF CHILD PSYCHOPATHOLOGY
items: ALVEOLAR RECRUITMENT MANEUVERS IN CARDIAC ICU PATIENTS: A LITERATURE REVIEW
items: THE RELATIONSHIP BETWEEN HIGH-PERFORMANCE SPORTS AND ANTERIOR CRUCIATE LIGAMENT (ACL) INJURIES: A SYSTEMATIC REVIEW
items: ANALYSIS OF THE PSYCHOSOCIAL DEVELOPMENT OF STUDENTS IN THE FIRST YEAR OF ELEMENTARY EDUCATION AT A SCHOOL IN THE MUNICIPALITY OF VOTUPORANGA-SP
items: GENES INVOLVED AND COMBINATION OF PHENOTYPICAL HETEROGENEITY IN PATIENTS DIAGNOSED WITH AUTISTIC SPECTRUM DISORDER (ASD): A LITERATURE REVIEW
items: IDENTIFICAÇÃO DO PERFIL GLICÊMICO E PRESSÓRICO DE OPERÁRIOS DE UMA FÁBRICA DE IMPLEMENTOS RODOVIÁRIOS DE VOTUPORANGA/SP
items: EFETIVIDADE DA ATENÇÃO PRIMÁRIA À SAÚDE NO CONTROLE DA PERIODONTITE: REVISÃO CRÍTICA COM ÊNFASE EM ESTRATÉGIAS DE PROMOÇÃO DA SAÚDE
items: HOME DENTAL CARE: THE EXPANSION OF PRIMARY CARE
items: SYSTEMATIZATION OF NURSING CARE FOR PATIENTS WITH HIV AND SYPHILIS: AN EXPERIENCE REPORT
items: ROLE OF MICROBIOTA-GUT-BRAIN AXIS IN AUTISM SPECTRUM DISORDER
items: INTERNAL AND EXTERNAL FACTORS RELATED TO BRACHYCEPHALY: AN INTEGRATIVE REVIEW
items: COMPLICATIONS ASSOCIATED WITH MANDIBULAR RECONSTRUCTION WITH ILIAC CREST BONE GRAFT: A CASE REPORT
items: INCIDENCE OF CONGENITAL HEART DISEASE IN THE MUNICIPALITIES OF NORTHWESTERN SÃO PAULO: AN ANALYSIS BASED ON DATASUS
items: ENDOMETRIOSIS AND EARLY DIAGNOSIS AND NEW APPROACHES TO TREATMENT
items: IDENTIFICAÇÃO DE INTERCORRÊNCIAS EM PROCEDIMENTOS ESTÉTICOS INVASIVOS
items: USE OF ZINC IN THE TREATMENT OF ACUTE DIARRHEA IN CHILDREN: LITERATURE REVIEW
items: CASE REPORT: MULTIDISCIPLINARY MANAGEMENT OF PHEOCHROMOCYTOMA IN A PREGNANT WOMAN WITH HYPERTENSIVE EMERGENCY

INFANT BACTERIAL MENINGITIS: DIAGNOSTIC, THERAPEUTIC, AND PROGNOSTIC CHALLENGES IN RECENT CASE REPORTS
type: item
description: Introduction: Pediatric bacterial meningitis is a rapidly progressive medical emergency with high morbidity and mortality, especially in neonates and young infants, due to immunological immaturity and the wide diversity of etiological agents. Despite advances in vaccination, the disease remains a major global public health challenge. Methods: This systematic review analyzed 20 case reports published over the last five years, selected from the PubMed, Medline, and LILACS databases. The descriptors “Meningitis, Bacterial,” “Pediatrics,” and “Clinical Diagnosis” were used. Of the 118 articles initially identified, after screening titles, abstracts, and full texts, 20 case reports met the inclusion criteria. Results: Fourteen distinct agents were identified, with predominance of Streptococcus pneumoniae (20%) and Streptococcus agalactiae (10%). Listeria monocytogenes and Mycoplasma hominis also accounted for 10% each. Children under 12 months of age represented nearly 50% of cases. The most frequent clinical manifestations were fever (85%), seizures (35%), vomiting (30%), and irritability (20%), while classic meningeal signs were present in only 20% of patients. The most commonly used empirical treatment was a combination of a third-generation cephalosporin and vancomycin, with therapeutic adjustment required in 70% of cases after culture and antibiogram. Eleven children recovered without sequelae, while nine developed neurological deficits, such as hearing loss, residual hydrocephalus, motor deficits, and cranial neuropathies, and one death was associated with non-K1 Escherichia coli. Conclusion: Pediatric bacterial meningitis shows marked etiological heterogeneity and clinical variation according to age group, hindering early diagnosis, particularly in neonates. Although appropriate treatment favors good outcomes, more virulent or resistant pathogens remain associated with significant neurological complications and mortality. Immediate initiation of empirical antibiot…
subject: Articles
  topic: section
subject: Bacterial Meningitis
  topic: keywords
subject: Pediatrics
  topic: keywords
subject: Etiological Agents
  topic: keywords
creator: Jascyone Barbosa Ritter
creator: Cândida Verônica de Andrade Paz
creator: Ianny Keruly Damião Pessoa
creator: Edilson Galeno de Sousa Junior
creator: Samara Tatielle Monteiro Gomes
rights: Copyright (c) 2026
date: 2026-01-12
publication date: 2026-01-12
starting page: e9016
ending page: e9016
doi: 10.56238/isevjhv5n1-001

EXCESSIVE SCREEN USE: PREVALENCE AND RISKS ASSOCIATED WITH CHILD DEVELOPMENT
type: item
description: The present study aimed to identify the consequences of excessive screen use in children, as well as to evaluate social interaction, measure Body Mass Index (BMI), and conduct a standard ophthalmological test using the Snellen Chart with 5th-grade elementary school students at CEM Prof. Valdir Gonçalves de Lima, in the municipality of Votuporanga, São Paulo, Brazil. The study is characterized as exploratory with a quantitative–qualitative approach, using questionnaires and interactive activities to foster bonding between the participants and the medical students.
subject: Articles
  topic: section
subject: Screens
  topic: keywords
subject: Childhood
  topic: keywords
subject: Social Interaction
  topic: keywords
subject: Visual Acuity
  topic: keywords
creator: Ana Beatriz Carneiro
creator: Bianca Portela Rosan
creator: Bruno Bomfim Lima
creator: Fabiana Elisa Rodrigues
creator: Fernanda Fernandes
creator: Gabriel Augusto Davila Sabino
creator: Isabela Magossi Queiroz
creator: João Álvaro Tavares de Andrade
creator: Maria Fernanda Maziero Oliveira da Silva
creator: Raí Isepão Barboza Silva
creator: Regiane Fernanda de Souza Barreto Rezende
rights: Copyright (c) 2025
date: 2025-12-19
publication date: 2025-12-19
starting page: e8790
ending page: e8790
doi: 10.56238/isevjhv4n6-003

MULTIDISCIPLINARY TREATMENT OF BONE SARCOMAS: OSTEOSARCOMA, CHONDROSARCOMA, AND EWING SARCOMA
type: item
description: Bone sarcomas, rare and aggressive neoplasms such as osteosarcoma, chondrosarcoma, and Ewing sarcoma, require a multidisciplinary and stratified oncologic and orthopedic approach. This review synthesizes evidence published between 2015 and 2025, addressing the surgical gold standard, neoadjuvant chemotherapy (MAP and VAC/IE regimens), radiotherapy, immune checkpoint inhibitor therapies (ICIs), and the emerging role of circulating molecular biomarkers (ctDNA). Recent studies highlight the importance of morphofunctional imaging characterization (CT and PET-CT) and molecular signatures (e.g., EWS-FLI1 translocation) to guide precise therapeutic decisions.
subject: Articles
  topic: section
subject: Osteosarcoma
  topic: keywords
subject: Chondrosarcoma
  topic: keywords
subject: Ewing Sarcoma
  topic: keywords
subject: Targeted Therapy
  topic: keywords
subject: EWS-FLI1
  topic: keywords
subject: Biomarkers
  topic: keywords
subject: Immunotherapy
  topic: keywords
creator: Fernanda Cristina Galerani Gualtieri Parpinelli
creator: Augustin Malzac
creator: Henrique Lucas Codognoto
creator: Cristina Jardelino de Lima
creator: Guilherme Banck
creator: Diogo Melo Mendo
rights: Copyright (c) 2025
date: 2025-11-27
publication date: 2025-11-27
starting page: e8618
ending page: e8618
doi: 10.56238/isevjhv4n6-002

RISKY SEXUAL BEHAVIORS IN UNIVERSITY STUDENTS ON THE AMERICAN CONTINENT
type: item
description: Introduction: Sexuality is determined by multiple factors. The knowledge and perceptions of the individual's environment will determine their behavior in this regard. Identifying the perceptions in a population that attends higher education is important to carry out specific prevention activities, since the repercussions of their sexual behavior are decisive for the public health of populations. Objective: Determine what are the perceptions and the main sexual risk behaviors in American university students. Method: Systematic review. The search was carried out in the Cochrane, Medigraphic and PubMed databases with the search words sexual behavior, college students, finding 25,821 results, filtered by language (English or Spanish), access to full text, year of publication (2016- 2021), geographic area (American continent) and sample (university population), resulting in n=12 articles. Results: most of the authors agree that American university students, despite having knowledge regarding sexuality and Sexually Transmitted Infections (STIs), do not carry out preventive actions, with a beginning of sexual life approximately at the age of fifteen and multiple partners. simultaneous; condom use is predominant as a method of family planning and sexting as a risky sexual behavior has become more important in recent years. Conclusions: the high prevalence of risk behaviors and the low use of diagnostic tests supports the fact that America is one of the continents with the most annual diagnoses of STIs in the world, with consequences that can be of varying severity and even fatal.
subject: Articles
  topic: section
subject: Sexual Behavior
  topic: keywords
subject: University Students
  topic: keywords
subject: Perceptions of Sexuality
  topic: keywords
creator: Tomasa de Los Angeles Jiménez Pirrón
creator: Sonia Rosa Roblero Ochoa
creator: Zally Patricia Mandujano Trujillo
creator: Rosa Martha Velasco Martínez
creator: Fátima Higuera Domínguez
creator: Itzel Castro Padilla
rights: Copyright (c) 2025
date: 2025-11-05
publication date: 2025-11-05
starting page: e8417
ending page: e8417
doi: 10.56238/isevjhv4n6-001

SPIRULINA (ARTHROSPIRA PLATENSIS): AN ALTERNATIVE SOURCE OF NUTRIENTS - A REVIEW
type: item
description: Spirulina (Arthrospira platensis) is a blue-green cyanobacterium that grows in fresh and salt water. It is known to be a rich source of nutrients, including proteins, vitamins, minerals, and antioxidants. One of its main applications is its use as nutritional supplement, where Spirulina is often consumed to its high protein content and other essential nutrients. It is especially popular among vegetarians and vegans due to its complete protein quality. Some studies suggest that Spirulina may have several health benefits, such as reducing cholesterol, controlling blood pressure, strengthening the immune system and protecting against cardiovascular diseases. It has also been reported to act as a detox agent, since Spirulina is known for its ability to detoxify the body, helping to remove heavy metals and toxins from the body. In the cosmetics field, due to its antioxidant and nourishing properties, Spirulina is used in several products, such as facial creams, hair masks, and body lotions to promote skin and hair health. It is also used in agriculture as an organic fertilizer and in animal feeding, especially in aquaculture, as a source of protein for fish and shrimp. In summary, Spirulina is a valuable source of nutrients and has a variety of applications, from nutritional supplements to cosmetics and agriculture. Its health benefits and potential for sustainable use make it a popular choice in many areas. Therefore, in this article we review the applications of Spirulina (Arthrospira platensis).
subject: Articles
  topic: section
subject: Arthrospira platensis
  topic: keywords
subject: Nutritional supplement
  topic: keywords
subject: Health
  topic: keywords
subject: Proteins
  topic: keywords
subject: Cosmetics
  topic: keywords
creator: Daniel Nascimento Motta
creator: Milena Gaion Malosso
creator: Edilson Pinto Barbosa
creator: Eliana de Macedo Medeiros
creator: Rosany Piccolotto Carvalho
rights: Copyright (c) 2025
date: 2025-10-28
publication date: 2025-10-28
starting page: e8339
ending page: e8339
doi: 10.56238/isevjhv4n5-005

CONSCIOUS SEDATION IN DENTAL PRACTICE: CLINICAL PHARMACOLOGICAL PERSPECTIVES
type: item
description: Conscious sedation is widely used in contemporary dentistry to manage anxiety and fear, ensuring greater comfort and safety during clinical care. This study aims to review recent literature on the clinical and pharmacological perspectives of conscious sedation, with an emphasis on pharmacological agents, routes of administration, indications, and safety protocols. This integrative review was conducted in the PubMed, SciELO, and BVS databases, covering publications published between 2020 and 2025. The results show that nitrous oxide and midazolam remain the most commonly used drugs, standing out for their efficacy and safety profile when administered by qualified professionals. Technological and pharmacological advances have allowed greater control of sedation levels and reduced adverse effects, consolidating conscious sedation as an essential resource in modern dental practice.
subject: Articles
  topic: section
subject: Conscious Sedation
  topic: keywords
subject: Dentistry
  topic: keywords
subject: Pharmacology
  topic: keywords
subject: Nitrous Oxide
  topic: keywords
subject: Midazolam
  topic: keywords
creator: Maria Josilaine das Neves de Carvalho
creator: Marcos Gustavo Oliveira da Silva
creator: Rafael Bruno Santiago Monteiro
creator: Ana Elizabete Jacob Pedrosa
creator: Jeyse Anne Vasconcelos da Silva
creator: Thalita Augusta Amorim Santos
creator: Édila Figuerêdo Feitosa Cavalcanti
creator: Josie Meneses Aguiar
rights: Copyright (c) 2025
date: 2025-10-16
publication date: 2025-10-16
starting page: e8273
ending page: e8273
doi: 10.56238/isevjhv4n5-004

ORAL SQUAMOUS PAPILLOMA ASSOCIATED WITH HPV: DIFFERENTIAL DIAGNOSIS WITH OTHER VERRUCOUS LESIONS
type: item
description: Oral squamous papilloma is a benign epithelial lesion primarily associated with human papillomavirus (HPV) infection, clinically characterized by verrucous or papillomatous projections affecting the tongue, palate, and buccal mucosa. Despite its non-neoplastic nature, it presents clinical similarities with other verrucous lesions of the oral cavity, such as verruca vulgaris, condyloma acuminata, focal epithelial hyperplasia, and verrucous carcinoma, making differential diagnosis a clinical and histopathological challenge. Recent studies indicate a higher prevalence of low-risk genotypes, such as HPV 6 and 11, in oral squamous papilloma, although high-risk types, such as HPV 16 and 18, may be associated with the potential for malignant transformation. The literature highlights the importance of detailed histopathological analysis, complemented by immunohistochemical tests and polymerase chain reaction (PCR), as fundamental tools for accurate diagnostic differentiation. Correct differentiation of oral squamous papilloma from other verrucous lesions enables appropriate therapeutic approaches, prevents erroneous approaches, and contributes to targeted clinical monitoring, with a direct impact on dental practice and the prevention of complications.
subject: Articles
  topic: section
subject: Oral Papilloma
  topic: keywords
subject: Human Papillomavirus
  topic: keywords
subject: Differential Diagnosis
  topic: keywords
subject: Oral Lesions
  topic: keywords
subject: Oral Pathology
  topic: keywords
creator: Daniela Knupp de Souza
creator: Clarice Janine Magalhães Nogueira
creator: Karen Caroline Viana da Silva
creator: Laís Gomes Silva Neves
creator: Mateus Maia Carneiro
creator: Vitoria Lorena de Oliveira Fonseca
rights: Copyright (c) 2025 Daniela Knupp de Souza, Clarice Janine Magalhães Nogueira, Karen Caroline Viana da Silva, Laís Gomes Silva Neves, Mateus Maia Carneiro, Vitoria Lorena de Oliveira Fonseca
date: 2025-09-29
publication date: 2025-09-29
starting page: e8148
ending page: e8148
doi: 10.56238/isevjhv4n5-003

Template para Autores
type: item
subject: Template para Autores
  topic: section
rights: Copyright (c) 2025
date: 2025-09-29
publication date: 2025-09-29

HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FINDINGS OF PLACENTAS IN PREGNANT PATIENTS WITH SARS-COV-2
type: item
description: Blackground: Due to the pandemic, different diagnostic studies are being carried out throughout the world to identify the virus in the first place, determine the accompanying symptoms and complications that can alter normal hemostasis in patients, and in our environment it is no different since pregnant women per se have a diminished immune system. Objective: determine the histopathological and Inmunohistochemical finding of the placentas in pregnant patients with Covid-19. Methods: a descriptive study of 30 patients was carried out at the Leonardo Martinez Valenzuela Hospital, San Pedro Sula, Honduras during three months of 2021, where a histopathological and inmunohistochemical study of the placentas of pregnant patients with Covi-19 was carrie out. Results: histopathological studies of the placentas found congestive, infectious and inflammatory , infectious, and congestive changes, immunohistochemical studies with RT-PCR on each of the placenta samples without finding evidence of vertical transmission. Discusion: the histopathological changes produced in the placentas by covid infection can determine the degree of affectation of the developing fetus.
subject: Articles
  topic: section
subject: Immunohistochemistry
  topic: keywords
subject: Pathology
  topic: keywords
subject: Placenta
  topic: keywords
subject: Pregnancy
  topic: keywords
subject: Covid-19
  topic: keywords
creator: Mario Roberto Pinto Romero
creator: Daniela Rosibel Martinez Caceres
rights: Copyright (c) 2025 Mario Roberto Pinto Romero, Daniela Rosibel Martinez Caceres
date: 2025-09-22
publication date: 2025-09-22
starting page: e8099
ending page: e8099
doi: 10.56238/isevjhv4n5-002

THE ROLE OF FORENSIC ANTHROPOLOGISTS: A REVIEW OF THE SITUATION IN BRAZIL
type: item
description: Forensic anthropology has been gaining importance in Brazil, for example, in the context of mass disasters, missing persons, and criminal investigations. One of the cornerstones of the forensic anthropologist's role is identification, and Brazil is no exception. The role of forensic anthropologists has been studied in various locations around the globe, such as Thailand and Australia. In this context, this scientific manuscript aims to analyze the role of forensic anthropologists in Brazil, describing the profession's main roles and clarifying similarities and differences in comparison to other countries. This study is a systematic and integrative literature review, following a pre-established protocol. The PubMed (MEDLINE) and LILACS databases were searched, supplemented by additional research. These searches in PubMed and LILACS yielded an initial number (n) of 104 studies. After removing duplicates, 99 studies were left. After reading titles and abstracts, 85 studies were excluded, leaving 14 articles for full reading. Finally, 13 studies were excluded, leaving 1 article. A complementary search included 5 more relevant studies, resulting in a final "n" of 6. Based on the results, combined with the discussion, it was possible to note that forensic anthropologists in Brazil play essential roles in identifying missing persons, both in criminal and mass disaster contexts. The field is gaining increasing relevance in Brazil, but still faces structural challenges. It is considered that further investment is needed to maintain this growth and overcome the remaining challenges regarding forensic anthropology infrastructure in Brazil. The results of this study should be interpreted in light of its limitations, which include the lack of quality analysis and the lack of paired analysis. There is a need for new systematic reviews on the topic, considering a paired review approach and quality analysis in order to achieve greater scientific rigor and quality in the synthesis o…
subject: Articles
  topic: section
subject: Forensic Anthropology
  topic: keywords
subject: Role (Figurative)
  topic: keywords
subject: Mass Disaster
  topic: keywords
subject: Victim Identification
  topic: keywords
subject: Brazil
  topic: keywords
creator: Andressa Carvalho de Oliveira
rights: Copyright (c) 2025 Andressa Carvalho de Oliveira
date: 2025-09-10
publication date: 2025-09-10
starting page: e8039
ending page: e8039
doi: 10.56238/isevjhv4n5-001

EFFECTIVENESS OF PRIMARY HEALTH CARE IN THE CONTROL OF PERIODONTITIS: A CRITICAL REVIEW WITH EMPHASIS ON HEALTH PROMOTION STRATEGIES
type: item
description: Periodontitis is one of the most prevalent oral diseases worldwide, with significant impacts on the overall health of patients, especially in vulnerable populations. Primary Health Care (PHC) has proven to be an effective approach to the control and prevention of this condition, through educational strategies, preventive interventions, and early treatments. Several studies show that the integration of oral health into public policies and primary health services contributes significantly to the reduction of periodontitis and other oral disease rates. Educational interventions, such as the promotion of supervised brushing and the application of sealants, have been shown to be effective, especially when health professionals are trained to implement these practices (Martins et al., 2014; Silva et al., 2020). In addition, patient adherence to oral health programs is essential for the success of prevention strategies, being a constant challenge in PHC practices (Freitas & Silva, 2015). This critical review discusses the effectiveness of preventive approaches to periodontitis in Primary Care, focusing on health promotion strategies and the barriers that prevent the implementation of more effective policies.
subject: Articles
  topic: section
subject: Periodontitis
  topic: keywords
subject: Primary Health Care
  topic: keywords
subject: Oral Health Promotion
  topic: keywords
subject: Prevention
  topic: keywords
creator: Maria Josilaine das Neves de Carvalho
creator: Marcos Gustavo Oliveira da Silva
creator: Adriana da Silva Cabral Gonçalves de Souza
creator: André Gustavo Belarquino de Araújo Barros
creator: Maria Zilda da Silva
creator: Lucivania Nunes Pereira Silva
creator: Arthur Santos Acácio
creator: Paloma Alves Moura
rights: Copyright (c) 2025 Maria Josilaine das Neves de Carvalho, Marcos Gustavo Oliveira da Silva, Adriana da Silva Cabral Gonçalves de Souza, André Gustavo Belarquino de Araújo Barros, Maria Zilda da Silva, Lucivania Nunes Pereira Silva, Arthur Santos Acácio, Paloma Alves Moura
date: 2025-07-22
publication date: 2025-07-22
starting page: 272
ending page: 284
doi: 10.56238/isevjhv4n4-006

THE ROLE OF THE PHYSICIAN IN THE MANAGEMENT OF STROKE: PATHOPHYSIOLOGY, DIAGNOSIS AND CURRENT THERAPEUTIC APPROACHES
type: item
description: It is hoped that this article can facilitate the understanding of stroke management, as well as clarify doubts on the subject. The general objective of this study is to understand the role of the physician in the management of stroke, its pathophysiology, how the diagnosis should be made, and the necessary therapeutic approaches. The aim is to provide a comprehensive and practical view for application in the clinical context.
subject: Articles
  topic: section
creator: Geovanna Araújo Maciel
creator: Daiane Furtado Maluf
creator: Romário Júlio da Costa Sales
creator: Ueverton Rodrigues de Sousa
creator: Letícia Almeida Quixabeira
creator: Ana Carolina Beltrami
creator: Marcia Caparroz Nogueira
creator: Ana Beatriz Sueza da Silveira
creator: Paloma do Nascimento Ribeiro
creator: Anna Claudia Espelho de Almeida
creator: Suzana Mateus Alexandrino de Brito
creator: Thiago dos Santos Silva
creator: Débora Priscilla Araújo Maciel
creator: Isabel Cristina Araújo Vieira
creator: Daniel Gonçalves De Melo
rights: Copyright (c) 2025 Geovanna Araújo Maciel, Daiane Furtado Maluf, Romário Júlio da Costa Sales, Ueverton Rodrigues de Sousa, Letícia Almeida Quixabeira, Ana Carolina Beltrami, Marcia Caparroz Nogueira, Ana Beatriz Sueza da Silveira, Paloma do Nascimento Ribeiro, Anna Claudia Espelho de Almeida, Suzana Mateus Alexandrino de Brito, Thiago dos Santos Silva, Débora Priscilla Araújo Maciel, Isabel Cristina Araújo Vieira, Daniel Gonçalves De Melo
date: 2025-07-21
publication date: 2025-07-21
starting page: 262
ending page: 271
doi: 10.56238/

GENES INVOLVED AND COMBINATION OF PHENOTYPIC HETEROGENEITY IN PATIENTS DIAGNOSED WITH AUTISM SPECTRUM DISORDER (ASD): A LITERATURE REVIEW
type: item
description: Autism Spectrum Disorder (ASD) is characterized by cognitive impairment and impairment in behavioral and social interaction. Of complex etiology, considering interactions between genetic and epigenetic factors. Objective: The research proposes to investigate the genetic contribution underlying Autism Spectrum Disorder (ASD). Methods: A systematic literature review methodology is used in the PubMed, Scientific Electronic Library Online (Scielo) and VHL databases via DeCS/MeSH descriptors in any language. Results and discussions: The findings highlight the strong predominance of genetic influences in ASD, evidencing the alteration of more than 800 documented genes, whose heritability is greater than 80%. Covering a diverse plexus regarding its functionality with changes in chromatin remodeling, transcription factors/regulators, mRNA traffic regulators, protein modification, cell proliferation, and synaptic architecture. Genomic interactions that include deletion, translocation, polymorphism and specific mutations found in the genes: MTHFR, GABRB3, RELN, OXTR, RTTN, SOCS6, CBLN2, and the alteration of the chromosomal chromosomes in the numbers :1, 2, 3, 7, 16, 22, with a predominance of 17, were highlighted. Responsible for altering the formation of proteins and neurotransmitters indispensable for the development of physical, social and behavioral skills. In addition, association with RETT and X-fragile syndromes. Conclusion: Therefore, this research highlights the genetic complexity of ASD with a high degree of heritability, the insufficiency of genetic testing, reliable biological markers, and the pressing need for additional advances in diagnosis, clinical management, and early therapeutic approaches.
subject: Articles
  topic: section
subject: Genetics
  topic: keywords
subject: Genes
  topic: keywords
subject: Autism
  topic: keywords
creator: Jéssica Altino Gomes de Almeida Albuquerque
creator: Caio Marques Porfirio
creator: Carol Marques Porfírio
creator: Fabiana Benigna Muniz de Sousa
creator: Leonardo Barbosa de Mariz Nogueira
creator: Marina de Fátima Nunes Fernandes de Lima
creator: Juannicelle Tenório Albuquerque Madruga Godoi
creator: Allan Almeida Albuquerque
rights: Copyright (c) 2025 Jéssica Altino Gomes de Almeida Albuquerque, Caio Marques Porfirio, Carol Marques Porfírio, Fabiana Benigna Muniz de Sousa, Leonardo Barbosa de Mariz Nogueira, Marina de Fátima Nunes Fernandes de Lima, Juannicelle Tenório Albuquerque Madruga Godoi, Allan Almeida Albuquerque
date: 2025-07-14
publication date: 2025-07-14
starting page: 253
ending page: 261
doi: 10.56238/isevjhv4n4-004

FROM PSYCHOSIS TO THE AUTISM SPECTRUM: A BRIEF HISTORY OF THE DIAGNOSTIC TRANSITION IN THE FIELD OF CHILD PSYCHOPATHOLOGY
type: item
description: This article analyzes the historical and discursive transition between the diagnoses of childhood psychosis and autism from DSM-III to V, exploring the formulations in psychiatric manuals and the impact of epistemological changes since the twentieth century. The article proposes that the notion of spectrum articulates a new regime of recognition for difference, while incorporating tensions between control, standardization, and subjective resistance in the context of treatments and public health policies.
subject: Articles
  topic: section
subject: Autism
  topic: keywords
subject: Psychosis
  topic: keywords
subject: Diagnosis
  topic: keywords
subject: Child Psychiatry
  topic: keywords
subject: Psychopathology
  topic: keywords
creator: Christian Ingo Lenz Dunker
creator: Mariana Haddad Rodotá Stéfano
rights: Copyright (c) 2025 Christian Ingo Lenz Dunker, Mariana Haddad Rodotá Stéfano
date: 2025-07-08
publication date: 2025-07-08
starting page: 232
ending page: 252
doi: 10.56238/isevjhv4n4-003

ALVEOLAR RECRUITMENT MANEUVERS IN CARDIAC ICU PATIENTS: A LITERATURE REVIEW
type: item
description: Heart diseases represent a worrying condition in ICU patients, and heart failure (HF) is one of the most common and aggravating heart diseases, as it compromises respiratory function. HF causes the accumulation of fluids in the lungs, generating pulmonary edema and, consequently, atelectasis, which collapses the alveoli. This collapse reduces gas exchange, aggravating hypoxemia and making it difficult for the patient to recover. Due to the importance of the theme, the study aims to identify how alveolar recruitment maneuvers can help in the treatment of patients in cardiology ICUs. A search for scientific articles was carried out in the PubMed, SciELO, Getinge, Artmed and ScienceDirect databases. Articles published in full, in English and Portuguese, that addressed cardiology ICU patients on mechanical ventilation after cardiac surgery, patients affected by ARDS, and ICU patients in whom alveolar recruitment maneuvers were adopted as a therapeutic measure were included in the search. Studies that did not use alveolar recruitment maneuvers as an intervention method were excluded. Alveolar recruitment maneuvers, associated with pulmonary protective ventilation strategies, can establish a good hemodynamic condition, reducing lung lesions and significantly increasing oxygenation levels.
subject: Articles
  topic: section
subject: Heart disease
  topic: keywords
subject: ICU
  topic: keywords
subject: Alveolar recruitment
  topic: keywords
creator: Hemily Maria Lopes de Oliveira
creator: Ianara Barros Albuquerque
creator: Julya Catarine Texeira Lima
creator: Vinnícius Gabriel dos Santos Conrado
rights: Copyright (c) 2025 Hemily Maria Lopes de Oliveira, Ianara Barros Albuquerque, Julya Catarine Texeira Lima , Vinnícius Gabriel dos Santos Conrado
date: 2025-07-07
publication date: 2025-07-07
starting page: 221
ending page: 231
doi: 10.56238/isevjhv4n4-002

THE RELATIONSHIP BETWEEN HIGH-PERFORMANCE SPORTS AND ANTERIOR CRUCIATE LIGAMENT (ACL) INJURIES: A SYSTEMATIC REVIEW
type: item
description: This article investigates the relationship between high-performance sports and Anterior Cruciate Ligament (ACL) injuries. The high incidence of these injuries, especially in sports involving rapid changes of direction, highlights the need to understand their mechanisms, risk factors, and prevention strategies. The research was conducted through an integrative literature review, with the aim of understanding the main risk factors, clinical consequences, and prevention strategies related to ACL injuries. Articles published between 2020 and 2025, selected from the PubMed and Virtual Health Library (VHL) databases, were analyzed. After applying inclusion and exclusion criteria, eight relevant studies were examined. The results indicate that most ACL injuries occur without direct contact, being attributed to biomechanical and neurocognitive factors, such as incorrect landings, inadequate hip flexion, and cognitive distractions during the game. Specific cases reveal that, in badminton, the scissor jump is frequently associated with the injury; In rugby, 75% of ruptures occur in the first 40 minutes of play; and in the WNBA, the average time to return from injury is 375 days. Furthermore, genetic studies suggest the possible influence of loci such as COL22A1 on susceptibility to ruptures. ACL injuries have a significant impact on athletes' sports careers and quality of life, resulting in prolonged absences and a high risk of recurrence. In view of this, the importance of adopting prevention programs focused on muscle strengthening, neuromotor control and movement reeducation is reinforced, as a way of preserving the performance and health of high-performance athletes.
subject: Articles
  topic: section
subject: ACL
  topic: keywords
subject: High-performance sports
  topic: keywords
subject: Non-contact injuries
  topic: keywords
subject: Injury prevention
  topic: keywords
subject: Risk factors
  topic: keywords
creator: Maria Clara Borges Toledo
creator: Stela Pires Azevedo Soares
creator: Ana Clara Almeida Ribeiro
creator: Izia Victória Conceição Moraes
creator: Wemily Rebello Fraportti
creator: David Salen Alves Azevedo
rights: Copyright (c) 2025 Maria Clara Borges Toledo, Stela Pires Azevedo Soares, Ana Clara Almeida Ribeiro, Izia Victória Conceição Moraes, Wemily Rebello Fraportti, David Salen Alves Azevedo
date: 2025-07-02
publication date: 2025-07-02
starting page: 208
ending page: 220
doi: 10.56238/isevjhv4n4-001

ANALYSIS OF THE PSYCHOSOCIAL DEVELOPMENT OF STUDENTS IN THE FIRST YEAR OF ELEMENTARY EDUCATION AT A SCHOOL IN THE MUNICIPALITY OF VOTUPORANGA-SP
type: item
description: It is essential to enable children to learn to name and express their emotions correctly so that they can reach the peak of their socio-emotional development in the future. Furthermore, it is observed that children demonstrate good levels of empathy and recognition of primary emotions, such as joy, sadness and anger. Despite this, in more complex emotional contexts, children need help and support so that they can understand and express their feelings appropriately. Unmonitored exposure to screens causes a delay in interpersonal interrelationships and, therefore, the learning of socio-emotional skills. Our results revealed that some children demonstrated sadness and frustration when they were removed from screens. For this reason, in an increasingly digital world, it is crucial that families and educators establish healthy limits for the use of technology, ensuring that they have time and space for experiences that foster adequate emotional and social development using other resources. The results highlight the importance of continually supporting the development of socio-emotional skills, in order to build a solid foundation for the improvement of essential skills such as self-control, empathy and conflict resolution, which are fundamental for adequate social and emotional development.
subject: Articles
  topic: section
subject: Mental health
  topic: keywords
subject: Screen control
  topic: keywords
subject: Socio-emotional development
  topic: keywords
creator: Aygla Salustiano Montanaro
creator: Catharine Müller dos Santos
creator: Felipe Borges Magalhães
creator: Gisele Casagrande Vieira
creator: Guilherme Roberto Gestal Madi Filho
creator: Júlia Bavaresco Borges
creator: Maria Clara Fernandes Venâncio
creator: Othávio Rocha de Souza
creator: Rafaela Sartori Sá
creator: Richard Franchetto Morgoni Stavarengo
creator: Victória Teresa Amaral Garcia
creator: Uderlei Doniseti Silveira Covizzi
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-06-30
publication date: 2025-06-30
starting page: 185
ending page: 207
doi: 10.56238/isevjhv4n3-004

GENES INVOLVED AND COMBINATION OF PHENOTYPICAL HETEROGENEITY IN PATIENTS DIAGNOSED WITH AUTISTIC SPECTRUM DISORDER (ASD): A LITERATURE REVIEW
type: item
description: Autism Spectrum Disorder (ASD) is characterized by cognitive impairment and impairment in behavioral and social interaction. Of complex etiology, considering interactions between genetic and epigenetic factors. Objective: The research proposes to investigate the genetic contribution underlying Autism Spectrum Disorder (ASD). Methods: A systematic literature review methodology is used in the PubMed, Scientific Electronic Library Online (Scielo) and VHL databases via DeCS/MeSH descriptors in any language. Results and discussions: The findings highlight the strong predominance of genetic influences in ASD, evidencing the alteration of more than 800 documented genes, whose heritability is greater than 80%. Covering a diverse plexus regarding its functionality with changes in chromatin remodeling, transcription factors/regulators, mRNA traffic regulators, protein modification, cell proliferation, and synaptic architecture. Genomic interactions that include deletion, translocation, polymorphism and specific mutations found in the genes: MTHFR, GABRB3, RELN, OXTR, RTTN, SOCS6, CBLN2, and the alteration of the chromosomal chromosomes in the numbers :1, 2, 3, 7, 16, 22, with a predominance of 17, were highlighted. Responsible for altering the formation of proteins and neurotransmitters indispensable for the development of physical, social and behavioral skills. In addition, association with RETT and X-fragile syndromes. Conclusion: Therefore, this research highlights the genetic complexity of ASD with a high degree of heritability, the insufficiency of genetic testing, reliable biological markers, and the pressing need for additional advances in diagnosis, clinical management, and early therapeutic approaches.
subject: Articles
  topic: section
subject: Genetics
  topic: keywords
subject: Genes
  topic: keywords
subject: Autism
  topic: keywords
creator: Jéssica Altino Gomes de Almeida Albuquerque
creator: Caio Marques Porfirio
creator: Carol Marques Porfírio
creator: Fabiana Benigna Muniz de Sousa
creator: Leonardo Barbosa de Mariz Nogueira
creator: Marina de Fátima Nunes Fernandes de Lima
creator: Juannicelle Tenório Albuquerque Madruga Godoi
creator: Allan Almeida Albuquerque
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-06-20
publication date: 2025-06-20
starting page: 177
ending page: 184
doi: 10.56238/

IDENTIFICAÇÃO DO PERFIL GLICÊMICO E PRESSÓRICO DE OPERÁRIOS DE UMA FÁBRICA DE IMPLEMENTOS RODOVIÁRIOS DE VOTUPORANGA/SP
type: item
description: No início dos anos 70, estudos apontaram que, apesar do maior poder socioeconômico dos homens, eles demonstraram maiores índices de morbimortalidade, principalmente devido a fatores culturais como o machismo. Essa situação é exacerbada pelo acesso tardio ao sistema de saúde e pela resistência masculina ao autocuidado. Doenças crônicas não transmissíveis (DCNT), como doenças cardíacas e diabetes, são responsáveis por 75% das mortes globais, afetando especialmente países de baixa e média renda. No Brasil, as DCNT causam mais de 74% das mortes, associadas ao tabagismo e consumo excessivo de álcool como principais fatores de risco. Para melhorar a saúde masculina, é essencial superar barreiras socioculturais e adaptar as estratégias de atenção à saúde. A presente pesquisa teve como objetivo identificar o perfil glicêmico e pressórico dos funcionários de uma indústria fabricante de implementos rodoviários em uma cidade do Noroeste paulista, com foco na população masculina. A metodologia adotada foi descritiva de caráter exploratório, com abordagem quanti-qualitativa, e incluiu a coleta de dados em uma indústria fabricante de implementos rodoviários. Foi aferida a pressão arterial, testes de glicemia capilar, calculo do índice de massa corporal (IMC) e investigações com relação aos hábitos de vida relacionados ao tabagismo e ao alcoolismo, correlacionando esses fatores com os perfis de glicemia e pressão arterial. Esperou-se, dentro dos resultados, obter dados para rastreio em relação à prevenção de doenças crônicas, como hipertensão e diabetes, promovendo uma melhoria na qualidade de vida desta população.
subject: Articles
  topic: section
subject: Saúde masculina
  topic: keywords
subject: Diabetes
  topic: keywords
subject: Hipertensão
  topic: keywords
subject: Doenças crônicas não transmissíveis
  topic: keywords
subject: Prevenção
  topic: keywords
creator: Erick Alexandre Cova Binati
creator: Gustavo Fávaro Sevestrin
creator: Júlia Cassiolato Junqueira Torquato
creator: Lívia Scalia
creator: Mariana Cortopasso da Silva
creator: Melissa Macedo Ferracini
creator: Mirella Andrela Zanchetta
creator: Paulo Capel Takassi
creator: Pedro Henrique Bonan Figueira
creator: Yasmin Zampieri Pacheco
creator: Roberto Carlos Grassi Malta
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-05-13
publication date: 2025-05-13
starting page: 154
ending page: 176
doi: 10.56238/isevjhv4n3-002

EFETIVIDADE DA ATENÇÃO PRIMÁRIA À SAÚDE NO CONTROLE DA PERIODONTITE: REVISÃO CRÍTICA COM ÊNFASE EM ESTRATÉGIAS DE PROMOÇÃO DA SAÚDE
type: item
description: A periodontite é uma das doenças bucais mais prevalentes mundialmente, com impactos significativos na saúde geral dos pacientes, especialmente em populações vulneráveis. A Atenção Primária à Saúde (APS) tem se mostrado uma abordagem eficaz para o controle e prevenção dessa condição, por meio de estratégias educativas, intervenções preventivas e tratamentos precoces. Diversos estudos evidenciam que a integração da saúde bucal nas políticas públicas e nos serviços de saúde primária contribui significativamente para a redução das taxas de periodontite e outras doenças bucais. As intervenções educativas, como a promoção da escovação supervisionada e a aplicação de selantes, têm demonstrado eficácia, especialmente quando os profissionais de saúde são capacitados para implementar essas práticas (Martins et al., 2014; Silva et al., 2020). Além disso, a adesão dos pacientes a programas de saúde bucal é essencial para o sucesso das estratégias de prevenção, sendo um desafio constante nas práticas da APS (Freitas & Silva, 2015). Esta revisão crítica discute a eficácia das abordagens preventivas da periodontite na Atenção Primária, com foco nas estratégias de promoção da saúde e nas barreiras que impedem a implementação de políticas mais eficazes.
subject: Articles
  topic: section
subject: Periodontite
  topic: keywords
subject: Atenção Primária à Saúde
  topic: keywords
subject: Promoção da Saúde Bucal
  topic: keywords
subject: Prevenção
  topic: keywords
creator: Maria Josilaine das Neves de Carvalho
creator: Marcos Gustavo Oliveira da Silva
creator: Adriana da Silva Cabral Gonçalves de Souza
creator: André Gustavo Belarquino de Araújo Barros
creator: Maria Zilda da Silva
creator: Lucivania Nunes Pereira Silva
creator: Arthur Santos Acácio
creator: Paloma Alves Moura
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-05-06
publication date: 2025-05-06
starting page: 142
ending page: 153
doi: 10.56238/isevjhv4n3-001

HOME DENTAL CARE: THE EXPANSION OF PRIMARY CARE
type: item
description: Home visits are an essential instrument of the Family Health Strategy (FHS), allowing direct interaction between health professionals and patients in their family environment. This article aims to report the performance of the Oral Health Team (OHT) of the João Mota Basic Health Unit (BHU), located in the urban area of Caruaru-PE, in home visits carried out in the second half of 2024, aimed at bedridden and domiciled patients. During these visits, the team performed basic dental procedures such as tooth extractions, supragingival scaling, and topical fluoride application. In addition to clinical actions, the OHT played an educational role, guiding caregivers on correct oral hygiene, including brushing technique and periodic toothbrush changes. The request for this demand came from the Community Health Agents, who identified the difficulty of this population in accessing the UBS due to reduced mobility. After the visits, an improvement in oral health conditions was observed and, consequently, in the quality of life of the patients, especially in terms of diet. The performance of the OHT in home visits demonstrates the application of the principle of equity in health, providing quality dental care to individuals in vulnerable situations. The team's intervention is essential to ensure access to oral health, improving quality of life and ensuring health rights for all patients.
subject: Articles
  topic: section
subject: Oral Health. Home visit. Primary Care. Equity in health. Family Health Strategy.
  topic: keywords
creator: Marcos Gustavo Oliveira da Silva
creator: Beatriz de Santana Marques
creator: Edlla Eracelly Costa de Lima
creator: Francisco José Macêdo da Silva
creator: Karollayne Alves da Silva Paiva
creator: Maria Josilaine das Neves de Carvalho
creator: Pedrícia Rita Soares de Lima
creator: Tamires Gomes de Miranda Oliveira
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-04-28
publication date: 2025-04-28
starting page: 126
ending page: 141
doi: 10.56238/isevjhv4n2-005

SYSTEMATIZATION OF NURSING CARE FOR PATIENTS WITH HIV AND SYPHILIS: AN EXPERIENCE REPORT
type: item
description: INTRODUCTION: Acquired immunodeficiency syndrome (AIDS) is characterized as a severe form of a set of diseases linked to infection by the human immunodeficiency virus (HIV). HIV belongs to the group of retroviruses (BRUNNER et al, 2019). It is transmitted through bodily fluids, through sexual intercourse with an HIV-positive partner, and through the use of intravenous or injectable substances, blood transfusions or contaminated blood products, children born to HIV-infected mothers, and health professionals exposed to biological materials from infected patients (BRUNNER et al, 2019).
subject: Articles
  topic: section
subject: Keywords: Nursing Care. HIV and Syphilis. Experience Report.
  topic: keywords
creator: André Nobre de Oliveira
creator: Gabrielly Sayuri Matos Toshiak
creator: Gabrielly Yuki da Gloria Yoneda Cirilli
creator: Isabella Grando Lima Benitez
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-04-16
publication date: 2025-04-16
starting page: 114
ending page: 125
doi: 10.56238/isevjhv4n2-004

ROLE OF MICROBIOTA-GUT-BRAIN AXIS IN AUTISM SPECTRUM DISORDER
type: item
description: Background: This narrative literature review shows a close link between autism spectrum disorder and the severity of gastrointestinal symptoms, as there is a two-way communicative linking known as the gut-brain axis, and a large amount of research shows the importance of a balanced microbiota to guarantee normal development and sustainment of brain function. Methods: A systematic review was performed utilizing the PubMed (Medline) database to explore literature published within the last 6 years, focusing on studies investigating the correlation between the gut-brain axis and autism spectrum disorder, with a specific emphasis on the gut microbiota. Results: Some studies findings demonstrate a decrease in bacterial diversity and also the influence of microbial metabolites associated with the development of ASD and the harshness of the symptoms. An imbalance in the gut microbial flora can result in dysbiosis, leading to diseases and overproduction of proinflammatory cytokines, affecting nutrition and immune responses. Although many studies involving microbiota transfer, vitamin A, the use of probiotics, and other kinds of nourishment are being held, there are no definitive or effective therapies for ASD yet. Conclusions: More studies are needed to understand the connection between the gut-microbiome-brain axis and ASD, as well as how dietary changes can improve ASD symptoms.
subject: Articles
  topic: section
subject: Gut-brain Axis
  topic: keywords
subject: Gastrointestinal tract
  topic: keywords
subject: Microbiota
  topic: keywords
subject: Autism
  topic: keywords
creator: João Víctor Ferreira Santos
creator: Mariana Heyden Barbosa
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-04-10
publication date: 2025-04-10
starting page: 102
ending page: 113
doi: 10.56238/isevjhv4n2-003

INTERNAL AND EXTERNAL FACTORS RELATED TO BRACHYCEPHALY: AN INTEGRATIVE REVIEW
type: item
description: Prenatal and gestational factors influence embryonic formation directly and indirectly. Its capabilities to influence cranial malformation are the subject of research around the world and a global understanding of this influence is needed. The present review seeks to compile and correlate the internal and external factors responsible for the presence of brachycephaly. To this end, studies were selected that were divided into two groups of triggering factors: external and internal. The literature contemplates that among the external factors: the maternal smoking habit, the time of delivery and the age of the parents are correlated factors. Among the internal factors are genetic factors, trisomy 21 and basilar invagination. Knowledge of these factors can contribute to the formation of screening, diagnosis, and early treatment policies.
subject: Articles
  topic: section
subject: Craniosynostosis
  topic: keywords
subject: Genetic Phenomena
  topic: keywords
subject: Congenital Abnormalities
  topic: keywords
creator: Leonardo Francisco Cesarino Mendonça
creator: Isabela Fontana de Souza
creator: Caio Felipe Pugliesi de Souza
creator: Eduardo César Silva Araújo
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-04-09
publication date: 2025-04-09
starting page: 96
ending page: 101
doi: 10.56238/isevjhv4n2-002

COMPLICATIONS ASSOCIATED WITH MANDIBULAR RECONSTRUCTION WITH ILIAC CREST BONE GRAFT: A CASE REPORT
type: item
description: The use of iliac crest bone grafts has become one of the main methods of mandibular bone reconstruction, due to factors that include anatomical similarity and resistance to masticatory forces. Several aspects are determinant for the success of this technique, including shape, location, and size of the bone defect; age, medical condition, and oral hygiene of the patient. In addition, the etiology of the fracture should be considered in the prognosis of surgical treatment. Fractures caused by firearm projectiles, for example, tend to result in postoperative infections, due to the contamination of the wound. The present study aims to present the use of iliac crest bone grafts and associated complications through a clinical case report. Patient M.R.S., male, victim of an accident caused by a firearm projectile in 2017, sought the Oral and Maxillofacial Surgery and Traumatology service of the General Hospital of the State of Bahia with pain in the left hemimandible. On physical examination, the patient presented atypical mobility on mandibular manipulation and the presence of a submandibular fistula on the left with serous drainage at milking. Computed tomography showed a bone defect in the mandibular body region with the presence of a fractured reconstruction plate. Reconstruction of the defect was performed with a free iliac crest graft and reconstruction plates. However, the patient developed a graft infection, and its removal was recommended, without further complications. Accurate diagnosis and planning, and good execution of the technique contribute to the success of the procedure. However, associated complications are possible, as with any surgical procedure.
subject: Articles
  topic: section
subject: Mandibular reconstruction
  topic: keywords
subject: Infections
  topic: keywords
subject: Complications
  topic: keywords
subject: Allografts
  topic: keywords
creator: Carolina Rosa Barros Oliveira
creator: Rair de Miranda Santos
creator: Elias Almeida dos Santos
creator: Maria Carolina Santos dos Santos
creator: Adriano Freitas de Assis
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-03-10
publication date: 2025-03-10
starting page: 83
ending page: 95
doi: 10.56238/isevjhv4n2-001

INCIDENCE OF CONGENITAL HEART DISEASE IN THE MUNICIPALITIES OF NORTHWESTERN SÃO PAULO: AN ANALYSIS BASED ON DATASUS
type: item
description: The chromosomopathies that generate congenital heart diseases represent one of the main challenges for neonatal public health in Brazil, affecting about 30 thousand newborns annually. Data from DATASUS and the Information System on Live Births (SINASC) indicate significant underreporting, with only 5.3% of the estimated cases officially registered. The global prevalence of 9 cases per 1,000 live births is used as a parameter to estimate the national figures, which point to a significant burden of the disease. About 40% of affected newborns require surgical intervention in the first year of life, highlighting the importance of early diagnosis and specialized follow-up. This article discusses the challenges related to data collection, the formulation of public policies, and strategies to improve the care of patients with chromosomal diseases in the Northwest of São Paulo.
subject: Articles
  topic: section
subject: Chromosomopathies
  topic: keywords
subject: Heart Diseases Congenital
  topic: keywords
subject: Neonatal Health
  topic: keywords
creator: Mariana Gatto Juliano
creator: Elis Daiane Teodoro
creator: Larissa Vilela Perroni Silva Soler
creator: Rafael Alves de Oliveira
creator: Cindy Larielli Vasconcelos
creator: Sthefany Cristine Avila Mendes
creator: Ana Clara Antonino Pereira
creator: Matheus Sousa Ferreira
creator: Lucas Martins Kamiyama
creator: Alba Regina de Abreu Lima
creator: Uderlei Doniseti Silveira Covizzi
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-02-20
publication date: 2025-02-20
starting page: 71
ending page: 81
doi: 10.56238/isevjhv4n1-006

ENDOMETRIOSIS AND EARLY DIAGNOSIS AND NEW APPROACHES TO TREATMENT
type: item
description: Endometriosis and uterine fibroids are common gynecological conditions that affect millions of women of reproductive age. Both conditions have a significant impact on quality of life and are associated with symptoms such as chronic pelvic pain, infertility and menstrual changes. This review article looks at advances in early diagnosis, highlighting the role of imaging tests, such as ultrasound and magnetic resonance imaging, and biological markers in the management of these conditions. It also explores new therapeutic approaches, including pharmacological treatments, such as selective hormone modulators, and minimally invasive techniques, such as fibroid embolization and laparoscopic excision of endometriosis. Integrating personalized strategies into care allows for better clinical outcomes and greater patient well-being.
subject: Articles
  topic: section
subject: Endometriosis
  topic: keywords
subject: Uterine Fibroids
  topic: keywords
subject: Early Diagnosis
  topic: keywords
subject: Innovative Therapies
  topic: keywords
subject: Laparoscopy
  topic: keywords
subject: Fibroid Embolization
  topic: keywords
subject: Quality of Life
  topic: keywords
subject: Infertility
  topic: keywords
creator: Thalita P. M. Alineri
creator: Délio T. Malaquias
creator: Myrian P. de M. Santos
creator: Keldna K. da S. Paiva
creator: Manuela H. Granieri
creator: Diego P. Mariz
creator: Giovana R. Victorello
creator: Laura de C. Ortega
creator: Sofia A. da S. Barros
creator: Erica M. F. Vão
creator: Giovana C. Yamashiro
creator: Aline C. C. da Silva
creator: Viviane F. Gomes
creator: Rubens R. Tudela
creator: Samantha R. G. Sanches
creator: José C. F. da Silva
creator: Vitória F. Moyses
creator: Giovana S. de Castro
creator: Ana L. C. Nascimento
creator: Leonardo T. da Silva
creator: Maria V. M. Xavier
creator: Lorena P. Viana
creator: Thiago A. Rochettti Bezerra
creator: Juliana F. Beltran Paschoal
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-02-12
publication date: 2025-02-12
starting page: 57
ending page: 70
doi: 10.56238/isevjhv4n1-005

IDENTIFICAÇÃO DE INTERCORRÊNCIAS EM PROCEDIMENTOS ESTÉTICOS INVASIVOS
type: item
description: Introdução: Os procedimentos estéticos ganham amplitude na sociedade a cada dia, com a grande demanda, deparamos com profissionais de diversos níveis de experiência e capacitação, juntamente a tais, o surgimento de intercorrências em procedimentos invasivos. Objetivo: O objetivo deste trabalho foi identificar as intercorrências em procedimentos estéticos invasivos relatados por profissionais deste ramo. Material e Método: Tratou-se de uma pesquisa descritiva e quantitativa, por meio de uma pesquisa de campo, com base no levantamento obtido pela utilização de um questionário online pelo Google Forms, onde se aplicou em profissionais do ramo da estética até obter-se 50 participantes. Resultados: De acordo com o perfil dos profissionais 68% atuam há 1 a 5 anos na área. Na pesquisa identificou-se como local mais acometido por intercorrências à face (40%) e os lábios (34%) e em relação aos procedimentos que as originaram, 24 profissionais relataram o ácido hialurônico como o mais presente diante a tais reações adversas, sendo assimetria a intercorrência mais encontrada. Conclusão: Pode-se concluir com a pesquisa a necessidade de conhecimento e capacitação para realização de procedimentos estéticos, assim como, resolver as intercorrências que podem acontecer durante os procedimentos e desta forma, executá-las com segurança e qualidade.
subject: Articles
  topic: section
subject: Toxina botulínica
  topic: keywords
subject: Ácido hialurônico
  topic: keywords
subject: Ptose palpebral
  topic: keywords
subject: Edema
  topic: keywords
subject: Lasers
  topic: keywords
creator: Gabriel Diniz
creator: Anderson Martelli
creator: Thaís Louise Soares
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-01-14
publication date: 2025-01-14
starting page: 41
ending page: 56
doi: 10.56238/isevjhv4n1-004

USE OF ZINC IN THE TREATMENT OF ACUTE DIARRHEA IN CHILDREN: LITERATURE REVIEW
type: item
description: Objective: To evaluate the effectiveness of zinc supplementation in the treatment of acute diarrhea in children, focusing on reducing severity, and duration and preventing new episodes. Methods: This is a literature review, using the Google Scholar, PUBMED, Scielo, and LILACS databases together with information from Manuals and Guides of the World Health Organization and Ministry of Health, obtaining 24 articles. Bibliographic Review: Acute diarrhea, characterized by three or more liquid bowel movements in 24 hours, is one of the main causes of infant mortality, especially in developing countries. Several studies show zinc supplementation as an effective measure in reducing the duration and severity of diarrheal episodes in childhood, in addition to preventing recurrences. In addition, its use appears to decrease the frequency and duration of bowel movements and reduce hospitalizations. In addition to its use in acute diarrhea, there appear to be benefits in cases of pneumonia and malaria. Although effective, mild adverse effects, such as vomiting, reduce treatment adherence, and further studies are needed to assess the minimum dose required. Conclusion: Zinc supplementation, recommended by the WHO since 2004, reduces the severity and duration of diarrhea in children. However, research is possible to improve the dose and minimize adverse effects.
subject: Articles
  topic: section
subject: Acute Diarrhea
  topic: keywords
subject: Zinc
  topic: keywords
subject: Child Health
  topic: keywords
creator: Rodrigo Horta de Souza Rosario
creator: Luiza Maia Zica
creator: Natalia Claret Torres Praça
creator: Leticia Maia Zica
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-01-08
publication date: 2025-01-08
starting page: 32
ending page: 40
doi: 10.56238/isevjhv4n1-003

CASE REPORT: MULTIDISCIPLINARY MANAGEMENT OF PHEOCHROMOCYTOMA IN A PREGNANT WOMAN WITH HYPERTENSIVE EMERGENCY
type: item
description: INTRODUCTION: Pheochromocytomas are rare tumors of the chromaffin cells of the sympathetic-adrenomedullary axis, which produce catecholamines and can cause severe, sustained, or paroxysmal arterial hypertension (Lenders et al., 2005; Neumann, Young, & Eng, 2019). Clinical manifestations typically occur between the third and fourth decades of life but can occur at any age and affect both sexes equally (Bravo & Tagle, 2003). The maximum incidence is between the third and fifth decades of life, with a mean age at diagnosis of 24.9 years in hereditary cases and 43.9 years in sporadic cases (Lucena et al., 2023).
subject: Articles
  topic: section
subject: Pheochromocytoma
  topic: keywords
subject: Hypertensive Emergency
  topic: keywords
subject: Acute Pulmonary Edema
  topic: keywords
subject: Pregnancy
  topic: keywords
subject: Multidisciplinary Approach
  topic: keywords
creator: Leonardo Gusmão Ramos
creator: Brian Damm Piassi
creator: Murilo Gusmão Ramos
creator: Dario Santuchi
creator: Sandro Mello Ferreira
creator: Ronaldo Jose de Souza
creator: Guilherme Boina Heleodoro
rights: Copyright (c) 2025 International Seven Journal of Health Research
date: 2025-01-08
publication date: 2025-01-08
starting page: 21
ending page: 31
doi: 10.56238/isevjhv4n1-002