International Seven Journal of Health Research
The International Seven Journal of Health (ISJH)- ISSN- 2764-9415 is a journal dedicated to the publication of articles and studies related to the health area on an international basis, with bilingual publications in English, Spanish and Portuguese.
BREAST IMPLANT-ASSOCIATED ANAPLASTIC LARGE CELL LYMPHOMA: CASE REPORT
Breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell neoplasm mainly related to the use of textured breast implants. It usually presents as a late periprosthetic seroma, occurring years after implant surgery. We report the case of a 45-year-old patient with a history of augmentation mammoplasty with polyurethane implants who developed a persistent late seroma. After prolonged clinical and radiological follow-up, aspiration of the periprosthetic fluid revealed CD30-positive malignant cells, confirming the diagnosis of BIA-ALCL. The patient underwent bilateral breast explantation with complete capsulectomy, with no evidence of residual neoplasia in the surgical specimens. This case highlights the importance of clinical suspicion and cytopathological analysis of periprosthetic fluid in patients with late seroma, enabling early diagnosis and appropriate treatment, with a direct impact on prognosis.
INFANT BACTERIAL MENINGITIS: DIAGNOSTIC, THERAPEUTIC, AND PROGNOSTIC CHALLENGES IN RECENT CASE REPORTS
Introduction: Pediatric bacterial meningitis is a rapidly progressive medical emergency with high morbidity and mortality, especially in neonates and young infants, due to immunological immaturity and the wide diversity of etiological agents. Despite advances in vaccination, the disease remains a major global public health challenge. Methods: This systematic review analyzed 20 case reports published over the last five years, selected from the PubMed, Medline, and LILACS databases. The descriptors “Meningitis, Bacterial,” “Pediatrics,” and “Clinical Diagnosis” were used. Of the 118 articles initially identified, after screening titles, abstracts, and full texts, 20 case reports met the inclusion criteria. Results: Fourteen distinct agents were identified, with predominance of Streptococcus pneumoniae (20%) and Streptococcus agalactiae (10%). Listeria monocytogenes and Mycoplasma hominis also accounted for 10% each. Children under 12 months of age represented nearly 50% of cases. The most frequent clinical manifestations were fever (85%), seizures (35%), vomiting (30%), and irritability (20%), while classic meningeal signs were present in only 20% of patients. The most commonly used empirical treatment was a combination of a third-generation cephalosporin and vancomycin, with therapeutic adjustment required in 70% of cases after culture and antibiogram. Eleven children recovered without sequelae, while nine developed neurological deficits, such as hearing loss, residual hydrocephalus, motor deficits, and cranial neuropathies, and one death was associated with non-K1 Escherichia coli. Conclusion: Pediatric bacterial meningitis shows marked etiological heterogeneity and clinical variation according to age group, hindering early diagnosis, particularly in neonates. Although appropriate treatment favors good outcomes, more virulent or resistant pathogens remain associated with significant neurological complications and mortality. Immediate initiation of empirical antibiotic therapy, followed by adjustment according to the isolated agent, is essential for a better prognosis. The expansion of vaccination coverage against S. pneumoniae, Haemophilus influenzae type b, and meningococcus is also emphasized as a fundamental measure for prevention and reduction of morbidity and mortality.
EXCESSIVE SCREEN USE: PREVALENCE AND RISKS ASSOCIATED WITH CHILD DEVELOPMENT
The present study aimed to identify the consequences of excessive screen use in children, as well as to evaluate social interaction, measure Body Mass Index (BMI), and conduct a standard ophthalmological test using the Snellen Chart with 5th-grade elementary school students at CEM Prof. Valdir Gonçalves de Lima, in the municipality of Votuporanga, São Paulo, Brazil. The study is characterized as exploratory with a quantitative–qualitative approach, using questionnaires and interactive activities to foster bonding between the participants and the medical students.
Maria Fernanda Maziero Oliveira da Silva
Regiane Fernanda de Souza Barreto Rezende
MULTIDISCIPLINARY TREATMENT OF BONE SARCOMAS: OSTEOSARCOMA, CHONDROSARCOMA, AND EWING SARCOMA
Bone sarcomas, rare and aggressive neoplasms such as osteosarcoma, chondrosarcoma, and Ewing sarcoma, require a multidisciplinary and stratified oncologic and orthopedic approach. This review synthesizes evidence published between 2015 and 2025, addressing the surgical gold standard, neoadjuvant chemotherapy (MAP and VAC/IE regimens), radiotherapy, immune checkpoint inhibitor therapies (ICIs), and the emerging role of circulating molecular biomarkers (ctDNA). Recent studies highlight the importance of morphofunctional imaging characterization (CT and PET-CT) and molecular signatures (e.g., EWS-FLI1 translocation) to guide precise therapeutic decisions.
Fernanda Cristina Galerani Gualtieri Parpinelli
RISKY SEXUAL BEHAVIORS IN UNIVERSITY STUDENTS ON THE AMERICAN CONTINENT
Introduction: Sexuality is determined by multiple factors. The knowledge and perceptions of the individual's environment will determine their behavior in this regard. Identifying the perceptions in a population that attends higher education is important to carry out specific prevention activities, since the repercussions of their sexual behavior are decisive for the public health of populations. Objective: Determine what are the perceptions and the main sexual risk behaviors in American university students. Method: Systematic review. The search was carried out in the Cochrane, Medigraphic and PubMed databases with the search words sexual behavior, college students, finding 25,821 results, filtered by language (English or Spanish), access to full text, year of publication (2016- 2021), geographic area (American continent) and sample (university population), resulting in n=12 articles. Results: most of the authors agree that American university students, despite having knowledge regarding sexuality and Sexually Transmitted Infections (STIs), do not carry out preventive actions, with a beginning of sexual life approximately at the age of fifteen and multiple partners. simultaneous; condom use is predominant as a method of family planning and sexting as a risky sexual behavior has become more important in recent years. Conclusions: the high prevalence of risk behaviors and the low use of diagnostic tests supports the fact that America is one of the continents with the most annual diagnoses of STIs in the world, with consequences that can be of varying severity and even fatal.
SPIRULINA (ARTHROSPIRA PLATENSIS): AN ALTERNATIVE SOURCE OF NUTRIENTS - A REVIEW
Spirulina (Arthrospira platensis) is a blue-green cyanobacterium that grows in fresh and salt water. It is known to be a rich source of nutrients, including proteins, vitamins, minerals, and antioxidants. One of its main applications is its use as nutritional supplement, where Spirulina is often consumed to its high protein content and other essential nutrients. It is especially popular among vegetarians and vegans due to its complete protein quality. Some studies suggest that Spirulina may have several health benefits, such as reducing cholesterol, controlling blood pressure, strengthening the immune system and protecting against cardiovascular diseases. It has also been reported to act as a detox agent, since Spirulina is known for its ability to detoxify the body, helping to remove heavy metals and toxins from the body. In the cosmetics field, due to its antioxidant and nourishing properties, Spirulina is used in several products, such as facial creams, hair masks, and body lotions to promote skin and hair health. It is also used in agriculture as an organic fertilizer and in animal feeding, especially in aquaculture, as a source of protein for fish and shrimp. In summary, Spirulina is a valuable source of nutrients and has a variety of applications, from nutritional supplements to cosmetics and agriculture. Its health benefits and potential for sustainable use make it a popular choice in many areas. Therefore, in this article we review the applications of Spirulina (Arthrospira platensis).
CONSCIOUS SEDATION IN DENTAL PRACTICE: CLINICAL PHARMACOLOGICAL PERSPECTIVES
Conscious sedation is widely used in contemporary dentistry to manage anxiety and fear, ensuring greater comfort and safety during clinical care. This study aims to review recent literature on the clinical and pharmacological perspectives of conscious sedation, with an emphasis on pharmacological agents, routes of administration, indications, and safety protocols. This integrative review was conducted in the PubMed, SciELO, and BVS databases, covering publications published between 2020 and 2025. The results show that nitrous oxide and midazolam remain the most commonly used drugs, standing out for their efficacy and safety profile when administered by qualified professionals. Technological and pharmacological advances have allowed greater control of sedation levels and reduced adverse effects, consolidating conscious sedation as an essential resource in modern dental practice.
ORAL SQUAMOUS PAPILLOMA ASSOCIATED WITH HPV: DIFFERENTIAL DIAGNOSIS WITH OTHER VERRUCOUS LESIONS
Oral squamous papilloma is a benign epithelial lesion primarily associated with human papillomavirus (HPV) infection, clinically characterized by verrucous or papillomatous projections affecting the tongue, palate, and buccal mucosa. Despite its non-neoplastic nature, it presents clinical similarities with other verrucous lesions of the oral cavity, such as verruca vulgaris, condyloma acuminata, focal epithelial hyperplasia, and verrucous carcinoma, making differential diagnosis a clinical and histopathological challenge. Recent studies indicate a higher prevalence of low-risk genotypes, such as HPV 6 and 11, in oral squamous papilloma, although high-risk types, such as HPV 16 and 18, may be associated with the potential for malignant transformation. The literature highlights the importance of detailed histopathological analysis, complemented by immunohistochemical tests and polymerase chain reaction (PCR), as fundamental tools for accurate diagnostic differentiation. Correct differentiation of oral squamous papilloma from other verrucous lesions enables appropriate therapeutic approaches, prevents erroneous approaches, and contributes to targeted clinical monitoring, with a direct impact on dental practice and the prevention of complications.
Copyright (c) 2025 Daniela Knupp de Souza, Clarice Janine Magalhães Nogueira, Karen Caroline Viana da Silva, Laís Gomes Silva Neves, Mateus Maia Carneiro, Vitoria Lorena de Oliveira Fonseca
HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FINDINGS OF PLACENTAS IN PREGNANT PATIENTS WITH SARS-COV-2
Blackground: Due to the pandemic, different diagnostic studies are being carried out throughout the world to identify the virus in the first place, determine the accompanying symptoms and complications that can alter normal hemostasis in patients, and in our environment it is no different since pregnant women per se have a diminished immune system. Objective: determine the histopathological and Inmunohistochemical finding of the placentas in pregnant patients with Covid-19. Methods: a descriptive study of 30 patients was carried out at the Leonardo Martinez Valenzuela Hospital, San Pedro Sula, Honduras during three months of 2021, where a histopathological and inmunohistochemical study of the placentas of pregnant patients with Covi-19 was carrie out. Results: histopathological studies of the placentas found congestive, infectious and inflammatory , infectious, and congestive changes, immunohistochemical studies with RT-PCR on each of the placenta samples without finding evidence of vertical transmission. Discusion: the histopathological changes produced in the placentas by covid infection can determine the degree of affectation of the developing fetus.
Copyright (c) 2025 Mario Roberto Pinto Romero, Daniela Rosibel Martinez Caceres
THE ROLE OF FORENSIC ANTHROPOLOGISTS: A REVIEW OF THE SITUATION IN BRAZIL
Forensic anthropology has been gaining importance in Brazil, for example, in the context of mass disasters, missing persons, and criminal investigations. One of the cornerstones of the forensic anthropologist's role is identification, and Brazil is no exception. The role of forensic anthropologists has been studied in various locations around the globe, such as Thailand and Australia. In this context, this scientific manuscript aims to analyze the role of forensic anthropologists in Brazil, describing the profession's main roles and clarifying similarities and differences in comparison to other countries. This study is a systematic and integrative literature review, following a pre-established protocol. The PubMed (MEDLINE) and LILACS databases were searched, supplemented by additional research. These searches in PubMed and LILACS yielded an initial number (n) of 104 studies. After removing duplicates, 99 studies were left. After reading titles and abstracts, 85 studies were excluded, leaving 14 articles for full reading. Finally, 13 studies were excluded, leaving 1 article. A complementary search included 5 more relevant studies, resulting in a final "n" of 6. Based on the results, combined with the discussion, it was possible to note that forensic anthropologists in Brazil play essential roles in identifying missing persons, both in criminal and mass disaster contexts. The field is gaining increasing relevance in Brazil, but still faces structural challenges. It is considered that further investment is needed to maintain this growth and overcome the remaining challenges regarding forensic anthropology infrastructure in Brazil. The results of this study should be interpreted in light of its limitations, which include the lack of quality analysis and the lack of paired analysis. There is a need for new systematic reviews on the topic, considering a paired review approach and quality analysis in order to achieve greater scientific rigor and quality in the synthesis of evidence.
Copyright (c) 2025 Andressa Carvalho de Oliveira
EFFECTIVENESS OF PRIMARY HEALTH CARE IN THE CONTROL OF PERIODONTITIS: A CRITICAL REVIEW WITH EMPHASIS ON HEALTH PROMOTION STRATEGIES
Periodontitis is one of the most prevalent oral diseases worldwide, with significant impacts on the overall health of patients, especially in vulnerable populations. Primary Health Care (PHC) has proven to be an effective approach to the control and prevention of this condition, through educational strategies, preventive interventions, and early treatments. Several studies show that the integration of oral health into public policies and primary health services contributes significantly to the reduction of periodontitis and other oral disease rates. Educational interventions, such as the promotion of supervised brushing and the application of sealants, have been shown to be effective, especially when health professionals are trained to implement these practices (Martins et al., 2014; Silva et al., 2020). In addition, patient adherence to oral health programs is essential for the success of prevention strategies, being a constant challenge in PHC practices (Freitas & Silva, 2015). This critical review discusses the effectiveness of preventive approaches to periodontitis in Primary Care, focusing on health promotion strategies and the barriers that prevent the implementation of more effective policies.
Adriana da Silva Cabral Gonçalves de Souza
André Gustavo Belarquino de Araújo Barros
Copyright (c) 2025 Maria Josilaine das Neves de Carvalho, Marcos Gustavo Oliveira da Silva, Adriana da Silva Cabral Gonçalves de Souza, André Gustavo Belarquino de Araújo Barros, Maria Zilda da Silva, Lucivania Nunes Pereira Silva, Arthur Santos Acácio, Paloma Alves Moura
THE ROLE OF THE PHYSICIAN IN THE MANAGEMENT OF STROKE: PATHOPHYSIOLOGY, DIAGNOSIS AND CURRENT THERAPEUTIC APPROACHES
It is hoped that this article can facilitate the understanding of stroke management, as well as clarify doubts on the subject. The general objective of this study is to understand the role of the physician in the management of stroke, its pathophysiology, how the diagnosis should be made, and the necessary therapeutic approaches. The aim is to provide a comprehensive and practical view for application in the clinical context.
Copyright (c) 2025 Geovanna Araújo Maciel, Daiane Furtado Maluf, Romário Júlio da Costa Sales, Ueverton Rodrigues de Sousa, Letícia Almeida Quixabeira, Ana Carolina Beltrami, Marcia Caparroz Nogueira, Ana Beatriz Sueza da Silveira, Paloma do Nascimento Ribeiro, Anna Claudia Espelho de Almeida, Suzana Mateus Alexandrino de Brito, Thiago dos Santos Silva, Débora Priscilla Araújo Maciel, Isabel Cristina Araújo Vieira, Daniel Gonçalves De Melo
GENES INVOLVED AND COMBINATION OF PHENOTYPIC HETEROGENEITY IN PATIENTS DIAGNOSED WITH AUTISM SPECTRUM DISORDER (ASD): A LITERATURE REVIEW
Autism Spectrum Disorder (ASD) is characterized by cognitive impairment and impairment in behavioral and social interaction. Of complex etiology, considering interactions between genetic and epigenetic factors. Objective: The research proposes to investigate the genetic contribution underlying Autism Spectrum Disorder (ASD). Methods: A systematic literature review methodology is used in the PubMed, Scientific Electronic Library Online (Scielo) and VHL databases via DeCS/MeSH descriptors in any language. Results and discussions: The findings highlight the strong predominance of genetic influences in ASD, evidencing the alteration of more than 800 documented genes, whose heritability is greater than 80%. Covering a diverse plexus regarding its functionality with changes in chromatin remodeling, transcription factors/regulators, mRNA traffic regulators, protein modification, cell proliferation, and synaptic architecture. Genomic interactions that include deletion, translocation, polymorphism and specific mutations found in the genes: MTHFR, GABRB3, RELN, OXTR, RTTN, SOCS6, CBLN2, and the alteration of the chromosomal chromosomes in the numbers :1, 2, 3, 7, 16, 22, with a predominance of 17, were highlighted. Responsible for altering the formation of proteins and neurotransmitters indispensable for the development of physical, social and behavioral skills. In addition, association with RETT and X-fragile syndromes. Conclusion: Therefore, this research highlights the genetic complexity of ASD with a high degree of heritability, the insufficiency of genetic testing, reliable biological markers, and the pressing need for additional advances in diagnosis, clinical management, and early therapeutic approaches.
Jéssica Altino Gomes de Almeida Albuquerque
Marina de Fátima Nunes Fernandes de Lima
Juannicelle Tenório Albuquerque Madruga Godoi
Copyright (c) 2025 Jéssica Altino Gomes de Almeida Albuquerque, Caio Marques Porfirio, Carol Marques Porfírio, Fabiana Benigna Muniz de Sousa, Leonardo Barbosa de Mariz Nogueira, Marina de Fátima Nunes Fernandes de Lima, Juannicelle Tenório Albuquerque Madruga Godoi, Allan Almeida Albuquerque
FROM PSYCHOSIS TO THE AUTISM SPECTRUM: A BRIEF HISTORY OF THE DIAGNOSTIC TRANSITION IN THE FIELD OF CHILD PSYCHOPATHOLOGY
This article analyzes the historical and discursive transition between the diagnoses of childhood psychosis and autism from DSM-III to V, exploring the formulations in psychiatric manuals and the impact of epistemological changes since the twentieth century. The article proposes that the notion of spectrum articulates a new regime of recognition for difference, while incorporating tensions between control, standardization, and subjective resistance in the context of treatments and public health policies.
Copyright (c) 2025 Christian Ingo Lenz Dunker, Mariana Haddad Rodotá Stéfano
ALVEOLAR RECRUITMENT MANEUVERS IN CARDIAC ICU PATIENTS: A LITERATURE REVIEW
Heart diseases represent a worrying condition in ICU patients, and heart failure (HF) is one of the most common and aggravating heart diseases, as it compromises respiratory function. HF causes the accumulation of fluids in the lungs, generating pulmonary edema and, consequently, atelectasis, which collapses the alveoli. This collapse reduces gas exchange, aggravating hypoxemia and making it difficult for the patient to recover. Due to the importance of the theme, the study aims to identify how alveolar recruitment maneuvers can help in the treatment of patients in cardiology ICUs. A search for scientific articles was carried out in the PubMed, SciELO, Getinge, Artmed and ScienceDirect databases. Articles published in full, in English and Portuguese, that addressed cardiology ICU patients on mechanical ventilation after cardiac surgery, patients affected by ARDS, and ICU patients in whom alveolar recruitment maneuvers were adopted as a therapeutic measure were included in the search. Studies that did not use alveolar recruitment maneuvers as an intervention method were excluded. Alveolar recruitment maneuvers, associated with pulmonary protective ventilation strategies, can establish a good hemodynamic condition, reducing lung lesions and significantly increasing oxygenation levels.
Copyright (c) 2025 Hemily Maria Lopes de Oliveira, Ianara Barros Albuquerque, Julya Catarine Texeira Lima , Vinnícius Gabriel dos Santos Conrado
THE RELATIONSHIP BETWEEN HIGH-PERFORMANCE SPORTS AND ANTERIOR CRUCIATE LIGAMENT (ACL) INJURIES: A SYSTEMATIC REVIEW
This article investigates the relationship between high-performance sports and Anterior Cruciate Ligament (ACL) injuries. The high incidence of these injuries, especially in sports involving rapid changes of direction, highlights the need to understand their mechanisms, risk factors, and prevention strategies. The research was conducted through an integrative literature review, with the aim of understanding the main risk factors, clinical consequences, and prevention strategies related to ACL injuries. Articles published between 2020 and 2025, selected from the PubMed and Virtual Health Library (VHL) databases, were analyzed. After applying inclusion and exclusion criteria, eight relevant studies were examined. The results indicate that most ACL injuries occur without direct contact, being attributed to biomechanical and neurocognitive factors, such as incorrect landings, inadequate hip flexion, and cognitive distractions during the game. Specific cases reveal that, in badminton, the scissor jump is frequently associated with the injury; In rugby, 75% of ruptures occur in the first 40 minutes of play; and in the WNBA, the average time to return from injury is 375 days. Furthermore, genetic studies suggest the possible influence of loci such as COL22A1 on susceptibility to ruptures. ACL injuries have a significant impact on athletes' sports careers and quality of life, resulting in prolonged absences and a high risk of recurrence. In view of this, the importance of adopting prevention programs focused on muscle strengthening, neuromotor control and movement reeducation is reinforced, as a way of preserving the performance and health of high-performance athletes.
Copyright (c) 2025 Maria Clara Borges Toledo, Stela Pires Azevedo Soares, Ana Clara Almeida Ribeiro, Izia Victória Conceição Moraes, Wemily Rebello Fraportti, David Salen Alves Azevedo
ANALYSIS OF THE PSYCHOSOCIAL DEVELOPMENT OF STUDENTS IN THE FIRST YEAR OF ELEMENTARY EDUCATION AT A SCHOOL IN THE MUNICIPALITY OF VOTUPORANGA-SP
It is essential to enable children to learn to name and express their emotions correctly so that they can reach the peak of their socio-emotional development in the future. Furthermore, it is observed that children demonstrate good levels of empathy and recognition of primary emotions, such as joy, sadness and anger. Despite this, in more complex emotional contexts, children need help and support so that they can understand and express their feelings appropriately. Unmonitored exposure to screens causes a delay in interpersonal interrelationships and, therefore, the learning of socio-emotional skills. Our results revealed that some children demonstrated sadness and frustration when they were removed from screens. For this reason, in an increasingly digital world, it is crucial that families and educators establish healthy limits for the use of technology, ensuring that they have time and space for experiences that foster adequate emotional and social development using other resources. The results highlight the importance of continually supporting the development of socio-emotional skills, in order to build a solid foundation for the improvement of essential skills such as self-control, empathy and conflict resolution, which are fundamental for adequate social and emotional development.
Copyright (c) 2025 International Seven Journal of Health Research
GENES INVOLVED AND COMBINATION OF PHENOTYPICAL HETEROGENEITY IN PATIENTS DIAGNOSED WITH AUTISTIC SPECTRUM DISORDER (ASD): A LITERATURE REVIEW
IDENTIFICAÇÃO DO PERFIL GLICÊMICO E PRESSÓRICO DE OPERÁRIOS DE UMA FÁBRICA DE IMPLEMENTOS RODOVIÁRIOS DE VOTUPORANGA/SP
No início dos anos 70, estudos apontaram que, apesar do maior poder socioeconômico dos homens, eles demonstraram maiores índices de morbimortalidade, principalmente devido a fatores culturais como o machismo. Essa situação é exacerbada pelo acesso tardio ao sistema de saúde e pela resistência masculina ao autocuidado. Doenças crônicas não transmissíveis (DCNT), como doenças cardíacas e diabetes, são responsáveis por 75% das mortes globais, afetando especialmente países de baixa e média renda. No Brasil, as DCNT causam mais de 74% das mortes, associadas ao tabagismo e consumo excessivo de álcool como principais fatores de risco. Para melhorar a saúde masculina, é essencial superar barreiras socioculturais e adaptar as estratégias de atenção à saúde. A presente pesquisa teve como objetivo identificar o perfil glicêmico e pressórico dos funcionários de uma indústria fabricante de implementos rodoviários em uma cidade do Noroeste paulista, com foco na população masculina. A metodologia adotada foi descritiva de caráter exploratório, com abordagem quanti-qualitativa, e incluiu a coleta de dados em uma indústria fabricante de implementos rodoviários. Foi aferida a pressão arterial, testes de glicemia capilar, calculo do índice de massa corporal (IMC) e investigações com relação aos hábitos de vida relacionados ao tabagismo e ao alcoolismo, correlacionando esses fatores com os perfis de glicemia e pressão arterial. Esperou-se, dentro dos resultados, obter dados para rastreio em relação à prevenção de doenças crônicas, como hipertensão e diabetes, promovendo uma melhoria na qualidade de vida desta população.
EFETIVIDADE DA ATENÇÃO PRIMÁRIA À SAÚDE NO CONTROLE DA PERIODONTITE: REVISÃO CRÍTICA COM ÊNFASE EM ESTRATÉGIAS DE PROMOÇÃO DA SAÚDE
A periodontite é uma das doenças bucais mais prevalentes mundialmente, com impactos significativos na saúde geral dos pacientes, especialmente em populações vulneráveis. A Atenção Primária à Saúde (APS) tem se mostrado uma abordagem eficaz para o controle e prevenção dessa condição, por meio de estratégias educativas, intervenções preventivas e tratamentos precoces. Diversos estudos evidenciam que a integração da saúde bucal nas políticas públicas e nos serviços de saúde primária contribui significativamente para a redução das taxas de periodontite e outras doenças bucais. As intervenções educativas, como a promoção da escovação supervisionada e a aplicação de selantes, têm demonstrado eficácia, especialmente quando os profissionais de saúde são capacitados para implementar essas práticas (Martins et al., 2014; Silva et al., 2020). Além disso, a adesão dos pacientes a programas de saúde bucal é essencial para o sucesso das estratégias de prevenção, sendo um desafio constante nas práticas da APS (Freitas & Silva, 2015). Esta revisão crítica discute a eficácia das abordagens preventivas da periodontite na Atenção Primária, com foco nas estratégias de promoção da saúde e nas barreiras que impedem a implementação de políticas mais eficazes.
HOME DENTAL CARE: THE EXPANSION OF PRIMARY CARE
Home visits are an essential instrument of the Family Health Strategy (FHS), allowing direct interaction between health professionals and patients in their family environment. This article aims to report the performance of the Oral Health Team (OHT) of the João Mota Basic Health Unit (BHU), located in the urban area of Caruaru-PE, in home visits carried out in the second half of 2024, aimed at bedridden and domiciled patients. During these visits, the team performed basic dental procedures such as tooth extractions, supragingival scaling, and topical fluoride application. In addition to clinical actions, the OHT played an educational role, guiding caregivers on correct oral hygiene, including brushing technique and periodic toothbrush changes. The request for this demand came from the Community Health Agents, who identified the difficulty of this population in accessing the UBS due to reduced mobility. After the visits, an improvement in oral health conditions was observed and, consequently, in the quality of life of the patients, especially in terms of diet. The performance of the OHT in home visits demonstrates the application of the principle of equity in health, providing quality dental care to individuals in vulnerable situations. The team's intervention is essential to ensure access to oral health, improving quality of life and ensuring health rights for all patients.
Oral Health. Home visit. Primary Care. Equity in health. Family Health Strategy.
SYSTEMATIZATION OF NURSING CARE FOR PATIENTS WITH HIV AND SYPHILIS: AN EXPERIENCE REPORT
INTRODUCTION: Acquired immunodeficiency syndrome (AIDS) is characterized as a severe form of a set of diseases linked to infection by the human immunodeficiency virus (HIV). HIV belongs to the group of retroviruses (BRUNNER et al, 2019). It is transmitted through bodily fluids, through sexual intercourse with an HIV-positive partner, and through the use of intravenous or injectable substances, blood transfusions or contaminated blood products, children born to HIV-infected mothers, and health professionals exposed to biological materials from infected patients (BRUNNER et al, 2019).
Keywords: Nursing Care. HIV and Syphilis. Experience Report.
ROLE OF MICROBIOTA-GUT-BRAIN AXIS IN AUTISM SPECTRUM DISORDER
Background: This narrative literature review shows a close link between autism spectrum disorder and the severity of gastrointestinal symptoms, as there is a two-way communicative linking known as the gut-brain axis, and a large amount of research shows the importance of a balanced microbiota to guarantee normal development and sustainment of brain function. Methods: A systematic review was performed utilizing the PubMed (Medline) database to explore literature published within the last 6 years, focusing on studies investigating the correlation between the gut-brain axis and autism spectrum disorder, with a specific emphasis on the gut microbiota. Results: Some studies findings demonstrate a decrease in bacterial diversity and also the influence of microbial metabolites associated with the development of ASD and the harshness of the symptoms. An imbalance in the gut microbial flora can result in dysbiosis, leading to diseases and overproduction of proinflammatory cytokines, affecting nutrition and immune responses. Although many studies involving microbiota transfer, vitamin A, the use of probiotics, and other kinds of nourishment are being held, there are no definitive or effective therapies for ASD yet. Conclusions: More studies are needed to understand the connection between the gut-microbiome-brain axis and ASD, as well as how dietary changes can improve ASD symptoms.
INTERNAL AND EXTERNAL FACTORS RELATED TO BRACHYCEPHALY: AN INTEGRATIVE REVIEW
Prenatal and gestational factors influence embryonic formation directly and indirectly. Its capabilities to influence cranial malformation are the subject of research around the world and a global understanding of this influence is needed. The present review seeks to compile and correlate the internal and external factors responsible for the presence of brachycephaly. To this end, studies were selected that were divided into two groups of triggering factors: external and internal. The literature contemplates that among the external factors: the maternal smoking habit, the time of delivery and the age of the parents are correlated factors. Among the internal factors are genetic factors, trisomy 21 and basilar invagination. Knowledge of these factors can contribute to the formation of screening, diagnosis, and early treatment policies.
COMPLICATIONS ASSOCIATED WITH MANDIBULAR RECONSTRUCTION WITH ILIAC CREST BONE GRAFT: A CASE REPORT
The use of iliac crest bone grafts has become one of the main methods of mandibular bone reconstruction, due to factors that include anatomical similarity and resistance to masticatory forces. Several aspects are determinant for the success of this technique, including shape, location, and size of the bone defect; age, medical condition, and oral hygiene of the patient. In addition, the etiology of the fracture should be considered in the prognosis of surgical treatment. Fractures caused by firearm projectiles, for example, tend to result in postoperative infections, due to the contamination of the wound. The present study aims to present the use of iliac crest bone grafts and associated complications through a clinical case report. Patient M.R.S., male, victim of an accident caused by a firearm projectile in 2017, sought the Oral and Maxillofacial Surgery and Traumatology service of the General Hospital of the State of Bahia with pain in the left hemimandible. On physical examination, the patient presented atypical mobility on mandibular manipulation and the presence of a submandibular fistula on the left with serous drainage at milking. Computed tomography showed a bone defect in the mandibular body region with the presence of a fractured reconstruction plate. Reconstruction of the defect was performed with a free iliac crest graft and reconstruction plates. However, the patient developed a graft infection, and its removal was recommended, without further complications. Accurate diagnosis and planning, and good execution of the technique contribute to the success of the procedure. However, associated complications are possible, as with any surgical procedure.
INCIDENCE OF CONGENITAL HEART DISEASE IN THE MUNICIPALITIES OF NORTHWESTERN SÃO PAULO: AN ANALYSIS BASED ON DATASUS
The chromosomopathies that generate congenital heart diseases represent one of the main challenges for neonatal public health in Brazil, affecting about 30 thousand newborns annually. Data from DATASUS and the Information System on Live Births (SINASC) indicate significant underreporting, with only 5.3% of the estimated cases officially registered. The global prevalence of 9 cases per 1,000 live births is used as a parameter to estimate the national figures, which point to a significant burden of the disease. About 40% of affected newborns require surgical intervention in the first year of life, highlighting the importance of early diagnosis and specialized follow-up. This article discusses the challenges related to data collection, the formulation of public policies, and strategies to improve the care of patients with chromosomal diseases in the Northwest of São Paulo.
ENDOMETRIOSIS AND EARLY DIAGNOSIS AND NEW APPROACHES TO TREATMENT
Endometriosis and uterine fibroids are common gynecological conditions that affect millions of women of reproductive age. Both conditions have a significant impact on quality of life and are associated with symptoms such as chronic pelvic pain, infertility and menstrual changes. This review article looks at advances in early diagnosis, highlighting the role of imaging tests, such as ultrasound and magnetic resonance imaging, and biological markers in the management of these conditions. It also explores new therapeutic approaches, including pharmacological treatments, such as selective hormone modulators, and minimally invasive techniques, such as fibroid embolization and laparoscopic excision of endometriosis. Integrating personalized strategies into care allows for better clinical outcomes and greater patient well-being.
IDENTIFICAÇÃO DE INTERCORRÊNCIAS EM PROCEDIMENTOS ESTÉTICOS INVASIVOS
Introdução: Os procedimentos estéticos ganham amplitude na sociedade a cada dia, com a grande demanda, deparamos com profissionais de diversos níveis de experiência e capacitação, juntamente a tais, o surgimento de intercorrências em procedimentos invasivos. Objetivo: O objetivo deste trabalho foi identificar as intercorrências em procedimentos estéticos invasivos relatados por profissionais deste ramo. Material e Método: Tratou-se de uma pesquisa descritiva e quantitativa, por meio de uma pesquisa de campo, com base no levantamento obtido pela utilização de um questionário online pelo Google Forms, onde se aplicou em profissionais do ramo da estética até obter-se 50 participantes. Resultados: De acordo com o perfil dos profissionais 68% atuam há 1 a 5 anos na área. Na pesquisa identificou-se como local mais acometido por intercorrências à face (40%) e os lábios (34%) e em relação aos procedimentos que as originaram, 24 profissionais relataram o ácido hialurônico como o mais presente diante a tais reações adversas, sendo assimetria a intercorrência mais encontrada. Conclusão: Pode-se concluir com a pesquisa a necessidade de conhecimento e capacitação para realização de procedimentos estéticos, assim como, resolver as intercorrências que podem acontecer durante os procedimentos e desta forma, executá-las com segurança e qualidade.
USE OF ZINC IN THE TREATMENT OF ACUTE DIARRHEA IN CHILDREN: LITERATURE REVIEW
Objective: To evaluate the effectiveness of zinc supplementation in the treatment of acute diarrhea in children, focusing on reducing severity, and duration and preventing new episodes. Methods: This is a literature review, using the Google Scholar, PUBMED, Scielo, and LILACS databases together with information from Manuals and Guides of the World Health Organization and Ministry of Health, obtaining 24 articles. Bibliographic Review: Acute diarrhea, characterized by three or more liquid bowel movements in 24 hours, is one of the main causes of infant mortality, especially in developing countries. Several studies show zinc supplementation as an effective measure in reducing the duration and severity of diarrheal episodes in childhood, in addition to preventing recurrences. In addition, its use appears to decrease the frequency and duration of bowel movements and reduce hospitalizations. In addition to its use in acute diarrhea, there appear to be benefits in cases of pneumonia and malaria. Although effective, mild adverse effects, such as vomiting, reduce treatment adherence, and further studies are needed to assess the minimum dose required. Conclusion: Zinc supplementation, recommended by the WHO since 2004, reduces the severity and duration of diarrhea in children. However, research is possible to improve the dose and minimize adverse effects.