ANTICANCER ACTIVITY OF AMINOCHALCONES. SCIENTIFIC And TECHNOLOGICAL PROSPECTING

Abstract

Chalcones are a group of polyphenolic compounds derived from plants that exhibit a wide variety of biological activities, notably their cytotoxic capacity. The aim of the present study is to describe available articles regarding the cytotoxic characteristics of aminochalcones, and analized patent deposits this theme. The research was conducted by searching for the terms "Aminochalcones" AND/OR "cancer" "Biological action" AND/OR "Technological prospecting" in the Medical Subject Headings (MeSH) database as equated terms referring to the toxicological properties of aminochalcones. Patentaries bases using INPI, EPO, USPTO e WIPO was used to research inovation and Tecnology. Out of the 2,179 articles, only 10 were selected, with 2015 being the year of highest scientific productivity. Regarding patents, China ranks first, so out of the 112 patents observed, only 7 stand out due to their methodological relevance and innovations. The majority of researchers do not request patent deposits for the toxicological activity containing the study's technology. Patents, in summary, create favorable environments for the scientific and technological development of a country. Based on the data obtained, it is inferred that the quantity of publications regarding the anticancer properties of chalcones has increased over time; however, such compounds still have limited investigations, despite holding potential anticancer properties.