CRYOGLOBULINEMIC VASCULITIS SECONDARY TO PRIMARY SJOGREN'S SYNDROME: A CASE REPORT

Abstract

Sjögren's syndrome is a chronic autoimmune inflammatory disease characterized by functional impairment of the lacrimal and salivary glands. Clinical manifestations are divided into extraglandular and exocrine glandular. Cryoglobulinemic vasculitis, an example of an extraglandular clinical manifestation in Sjögren's disease, develops from the deposition of immune complexes containing cryoglobulins and, when present, may be associated with higher morbidity and mortality. The association between primary Sjögren's syndrome and cryoglobulinemic vasculitis is rare, and if diagnosed and treated late, it may progress to unfavorable outcomes with a significant impact on the patient's quality of life.

DOI: https://doi.org/10.56238/sevened2025.037-035