FOLIC ACID SUPPLEMENTATION AND REPRODUCTIVE HEALTH, TRANSCENDING THE PREVENTION OF NEURAL TUBE DEFECTS

Authors

  • Zulieth Lopez Arrieta
  • Elizabeth Brunal Amezquita
  • Isaac Rivera Diaz
  • Carolina Barrios Puerta
  • Verónica Benjumea Acosta
  • María José Zambrano Escorcia
  • Melanie Miranda Martínez
  • Angely Sofía Cardenas Acuña
  • Judith Carolina Trucco Luna

DOI:

https://doi.org/10.56238/sevened2026.009-072

Keywords:

Folic Acid, Reproductive Health, Pregnancy (DESC/MESH)

Abstract

Introduction: Folic acid is a vitamin that is traditionally prescribed to pregnant women in order to reduce the risk of neural tube abnormalities in the embryo, however, this practice should be reevaluated under the observation that many of the pregnancies are detected after the neural tube has formed and what would be the advantages or disadvantages after 28 days of gestation. 

Development: Scientific evidence supports that folic acid supplementation is relevant from gametogenesis to the day of delivery, because it contributes to sperm meiosis, oocyte maturation, embryonic tissue formation and the growth of fetal organs and structures. At present, studies on folic acid toxicity do not show conclusive results and further research is needed to elucidate this issue.

Conclusion: Adequate folic acid supplementation is important for reproductive health, directly influencing the proper development of gametes, the embryo/fetus, and the health of the pregnant woman.

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Published

2026-04-03

Issue

Pathways to Health: Innovations and Approaches in Health Sciences

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

Arrieta, Z. L., Amezquita, E. B., Diaz, I. R., Puerta, C. B., Acosta, V. B., Escorcia, M. J. Z., Martínez, M. M., Acuña, A. S. C., & Luna, J. C. T. (2026). FOLIC ACID SUPPLEMENTATION AND REPRODUCTIVE HEALTH, TRANSCENDING THE PREVENTION OF NEURAL TUBE DEFECTS. Seven Editora, 966-976. https://doi.org/10.56238/sevened2026.009-072