CASE REPORT: ACNE FULMINANS ASSOCIATED WITH ISOTRETINOIN
Keywords:
Acne Fulminans, Isotretinoin, Corticosteroid Therapy, Acne Fulminans Grade III, Exogenous HormonesAbstract
Introduction: The pathology of acne fulminans is based on the formation of Propionibacterium acnes as a superantigen that incites a highly inflammatory response in pilosebaceous follicles and musculoskeletal components. Common triggers are the introduction of isotretinoin and the indiscriminate use of exogenous hormones. The clinical presentation begins with comedones, papules, and pustules, progressing to multiple inflammatory lesions, as well as nodules and abscesses that can lead to areas of necrosis. Systemic symptoms such as fever and joint pain are frequently reported.
Objective: This study aims to review guidelines to improve the treatment outcomes of patients with Acne Fulminans.
Method: This study is a case report of isotretinoin-induced acne fulminans, focusing on clinical presentation, course, and management. Conducting literature reviews in PubMed, SciELO, and LILACS databases.
Conclusion: This study highlights the importance of early diagnosis and individualized treatment of acne fulminans, with an emphasis on corticosteroid therapy, isotretinoin discontinuation, and ongoing medical monitoring to prevent complications.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Lara Vitória Loução Durães Salgado, Marcella Pereira Palma, Yasmin Santos Sá, Giovana Ortega Praliola, Brunamelia de Oliveira Sattin, Nathalie Manoel Lopes, Thaís Rennó Campos, Rúbia Camargo dos Santos
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
