BIBLIOMETRIC SURVEY OF PUBLISHED ARTICLES ON THE MAIN BIOMODELS USED IN SCIENTIFIC RESEARCH

Abstract

In this chapter, we conducted a bibliometric survey of the number of articles published in indexed databases such as PubMed Medline, LILACS and Scielo in relation to the most commonly used biomodels for scientific purposes such as zebrafish, mouse, rat, rabbit, hamster and non-human primates. We also carried out a bibliometric survey of the number of articles published in different approaches using these models. Our methodology consisted of the use of descriptors and obtaining the total number of articles published for each designated descriptor. Our results demonstrated that the LILACS platform has the highest number of articles published for the respective biomodels, with the exception of non-human primates for which the PubMed Medline platform showed the highest number of published articles. We also addressed the use of these biomodels in the study of various areas such as cancer research, cardiovascular diseases, immune response, neurodegenerative diseases, behavioral changes and infectious diseases. The data show that in cancer studies the PubMed Medline platform presents the highest number of articles published for all biomodels. The same applies to the study of cardiovascular diseases. In the area of immune response, the LILACS platform presented the highest number of published articles for all biomodels, with the exception of non-human primates. The same profile was observed for the study of neurodegenerative diseases. Behavioral changes showed a higher number of articles published in the PubMed Medline platform for the biomodels zebrafish, mouse and non-human primate. The LILACS platform, on the other hand, showed a higher number of published articles for the biomodels rat, rabbit and hamster. In the study of infectious diseases, the LILACS platform presented a higher number of articles published for all biomodels, with the exception of non-human primates. Thus, we can conclude that, in general, the LILACS platform presents the highest number of published articles for the most commonly used biomodels for scientific purposes; however, depending on the approach, the PubMed Medline platform showed a higher number of published articles in the respective biomodels.